FREQUENCY OF HEPATITIS B AND C IN PATIENTS UNDERGOING ELECTIVE SURGERY

Authors

  • Muhammad Rafique Memon
  • Altaf Ahmed Shaikh
  • Aftab Ahmed Soomro
  • Saima Arshad
  • Qarib Abbas Shah

Abstract

Background: Viral Hepatitis (HBV and HCV) is a major health problem affecting approximately
two billion population worldwide. It is one of the single most important cause of chronic liver
disease and hepato-cellular carcinoma in Pakistan and worldwide and is now spreading beyond
endemic dimensions. This study was carried out to assess the frequency of Hepatitis B and C
infection in patients undergoing elective surgical operations, and to evaluate the associated risk
factors. Methods: This was a descriptive study, conducted at Surgical Department of Ghulam
Muhammad Mahar Medical College Hospital, Sukkur, from April 2009 to March 2010. All patients
who were admitted in the Surgical Department for elective surgical operations were included in the
study. The patients were screened for HBsAg and Anti-HCV using immunochromatography (ICT)
method. Those who were weak positive by ICT were further confirmed by ELISA. Results: Total
913 patients were admitted in Surgical Department during study period for elective operations and
were screened for HBsAg and Anti-HCV. Out of these, 572 (62.65%) were male and 341 (37.34%)
were female. Mean age of these patients was 40 years. After screening, 33 (3.61%) patients were
found HBsAg positive and 117 (12.8%) were Anti-HCV positive, while 9 (0.98%) were positive for
both. Hepatitis-B was found in 21 (2.3%) males and 12 (1.3%) females, and Hepatitis-C was found
in 68 (7.44%) males and 49 (5.36%) female patients. Parenteral injections by quacks, previous
surgery, blood transfusion and shaving by barbers were found to be the risk factors. Conclusion: Our
message is: '˜Prevention is better than cure'. It is essential to prevent spread of Hepatitis B and C by
screening every patient before surgery and counselling the patients. The doctors and paramedical
staff must follow proper ethical practice ensuring use of sterile disposables where indicated and
protecting patients and themselves from these viral infections.
Keywords: Hepatitis-B, Hepatitis-C, Screening, Surgical patients

References

Cusheri A. Acute and chronic hepatitis. In: Cusheri A, Steele JC,

Moosa AR. (Eds) Essential surgical practice. 5th Edition. Oxford

University Press; 2002. p.334-5.

EASL Jury. EASL International Consensus Conference on

Hepatitis B. 13-14 September 2002 Geneva, Switzerland. J

Hepatol 2003;38:533-40.

Khokhar N, Gill ML, Malik GL. General seroprevalance of

Hepatitis B and C infection in the population. J Coll Physicians

Surg Pak 2004;14:534-6.

Tanwani K, Ahmad N, Prevalence of Hepatitis B surface antigen

and anti-Hepatitis C virus in laboratory based at Islamabad. J

Surg 2000;19-20:25-9.

Supsa VE, Hadjipashali E, Hatzakis A. Prevalence of risk factors

and evaluation of a screening strategy for Hepatitis B and C viral

infections in healthy company employees. Euro J Epidemiol

;17:721-8.

Shah HN, Shabbir G. A review of published literature on

Hepatitis B and C virus prevalence in Pakistan. J Coll Physicians

Surg Pak 2002;12:368-71.

Sara H, Cody MD, Omana V, Meyers H, Bell BP, Shapiro CN, et

al. Hepatitis C virus transmission from an Anesthesiologist to a

patient. Arch Intern Med 2002;162:345-50.

Cardell K, Widell A, Frydén A, Akerlind B, Månsson AS,

Franzén S, et al. Nosocomial hepatitis C in a thoracic surgery

unit; retrospective findings generating a prospective study. J

Hosp Infect 2008;68:322-8.

Zubia M, Masood J, Khan RA, Shafiq ur Rehman. Screening for

Hepatitis B and C: a routine preoperative investigation? Pak J

Med Sci 2005;21:455-9.

Chaudry IA, Khan SS, Majrooh MA, Alvi AA. Seroprevalence

of hepatitis B and C among the patients reporting at surgical OPD

at fauji foundation Hospial Rawalpindi. Pak J Med Sci

;23:514-17.

Talpur AA, Ansari AG, Awan MS, Ghumro AA, Prevalence of

hepatitis B and C in surgical patients. Pak J Surg

:22(3):150-3.

Daudpota AQ, Soomro AW. Seroprevalence of hepatitis B and C

in surgical patients. Pak Med Sci 2008;24:483-4.

Taguchi S, Nishioka K, Kawaguchi R, Nakao Mankaom,

Watanabe I, Migita T. Epidemiological study of hepatitis B and

C in 34336 patients operated at Hiroshima Prefectual Hospital

during the period from 1993 to 2000. Masui 2004;53:696-700.

Yanaga K, Wakiyama S, Soejimay, Yoshizumi T, Nishizaki

T, Sugimachi K. Hepatitis C virus infection among Japanese

general surgical patients. World J Surg 1995;19:694-7.

Chaudhary IA, Khan SA, Samiullah. Should we do the hepatitis

B and C screening on each patient before surgery. Pak J Med Sci

;21:278-80.

Ali SA, Shaikh FA, Ahmed K. Prevalence of hepatitis B and C

virus in surgical patients. Pak J Surg 2007;23:109-12.

Weis ES, Makary MA, Wang T, Syin D, Pronovost PJ,

Chang D, et al. Prevalence of blood-borne pathogens in an

urban, university-based general surgical practice. Ann Surg

;241:803-7.

Meri Koulentaki, Maria Ergazaki, Joanna Moschandrea, Stelios

Spanoudakis, Nikolaos Tzagarakis. Prevalence of hepatitis B

and C workers in high-risk hospitalised patients in Grete. A

five-year observational study. BMC Public Health, 2001;1:17.

Khokhar N, Gill ML, Yawar A. Interspousal transmission of

Hepatitis C virus. J Coll Physicians Surg Pak 2005;15:587-9.

De Carli G, Puro V, Ippolito G; Studio Italiano Rischio

Occupazionale da HIV Group. Risk of hepatitis C virus

transmission following percutaneous exposure in healthcare

workers. Infection 2003;31(Suppl 2):22-7.

Moosa FA, Shaikh BA, Choudhry MS, Zuberi BF, Khan FW,

Sultan N. Frequency of hepatitis B and C in preoperative patients

for elective surgery. J Liaquat Uni Med Health Sci

;8(2):150-2.

J Ayub Med Coll Abbottabad 2010;22(2)

http://www.ayubmed.edu.pk/JAMC/PAST/22-2/Rafique.pdf

Bialek SR, Bower WA, Mottram K, Purchase D, Nakano

T, Nainan O, et al. Risk factors for Hepatitis B in an outbreak of

hepatitis B and D among injection drug users. J Urban Health

;82:468-78.

Yazdanpanah Y, De Carli G, Migueres B, Lot F, Campins

M, Colombo C, et al. Risk factors for hepatitis C virus

transmission to healthcare workers after occupational

exposure: A European case-control study. Clin Infect Dis

;41:1423-30.

Cholongitas E, Senzolo M, Patch D, Kwong K, Nikolopoulou

V, Leandro G, et al. Risk factors, sequential organ failure

assessment and model for end-stage liver disease scores for

predicting short term mortality in cirrhotic patients admitted to

intensive care unit. Aliment Pharmacol Ther 2006;23:883-93.

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Published

2010-06-01

How to Cite

Memon, M. R., Shaikh, A. A., Soomro, A. A., Arshad, S., & Shah, Q. A. (2010). FREQUENCY OF HEPATITIS B AND C IN PATIENTS UNDERGOING ELECTIVE SURGERY. Journal of Ayub Medical College Abbottabad, 22(2), 167–170. Retrieved from https://demo.ayubmed.edu.pk/jamc/index.php/jamc/article/view/3047