DIAGNOSTIC ACCURACY OF ENDOMETRIAL CURETTAGE IN ENDOMETRIAL PATHOLOGY
Abstract
Background: Abnormal uterine bleeding is one of the most frequent problems in life of an adult female.Uterine curettage or biopsy remains a preferred sampling procedure for diagnosis of the endometrialpathology. The objective of this study was to compare the sensitivity, specificity, positive and negativepredictive value of endometrial curettage. Patients and Methods: This validation study was carried outat the Department of Histopathology, Army Medical College Rawalpindi in collaboration with MilitaryHospital, Rawalpindi from January to December 2010. The study included 50 curettage and subsequenthysterectomy specimen of the same patients. Non-probability sampling technique was used to dividepatients into two groups with 50 patients in each group. One group was of endometrial curettage havingendometrial pathology (group A). Second group was of subsequent hysterectomy specimen of the samepatients (group B). Results: Endometrial curettage was found most accurate in diagnosing endometrialcarcinoma. Sensitivity of endometrial curettage was found to be 33% whereas specificity and positivepredictive value was found to be 100% each. Negative predictive value was found to be 93.1%.Conclusion: Endometrial biopsy is a sensitive and a specific test in and is accurate in diagnosingendometrial pathology. It is found most accurate in diagnosing endometrial carcinoma.Keywords: Dilation and curettage, Hysterectomy, Hormone imbalance, endometrium, dysfunctionaluterine bleeding, DUBReferences
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