HISTOPATHOLOGICAL PATTERN OF SOFT TISSUES TUMORS AND TUMOUR LIKE LESIONS IN THE PATHOLOGY DEPARTMENT OF LADY READING HOSPITAL PESHAWAR, PAKISTAN
Abstract
Background: Soft tissues tumours are tumours of mesenchymal origin excluding epithelial, skeletal tissue, reticuloendothelial system, brain coverings and solid viscera of the body. The objective of this study was to know the histopathological pattern of soft tissues tumours in the Pathology Department of Lady Reading Hospital Peshawar Khyber Pakhtunkhwa Pakistan. Methods: This descriptive study was conducted on retrospective data from January 2009 to December 2013. All the soft tissues biopsy specimens were received in 10% formalin, labelled, gross performed, sections processed in alcohol, xylene, wax, block prepared, frozen, microtome sections taken and processed for H&E staining, mounted and reported by a Histopathologist. The inclusion criteria was any sufficient soft tissue tumour biopsy specimen of any age, sex, location in body whereas the exclusion criteria was autolysed biopsy specimen. A minimum of four and maximum of eight sections and 5 micron thick were taken from each specimen. Results: A total of 267 soft tissues tumours biopsy specimens were received in the pathology laboratory with age range of 01 to 75 years, with mean age of 30.68±17.71 years. Male to female ratio was 1.13:1. Amongst the total, benign tumours were 176 (65.91%). Haemangioma, 73 (27.3%) was the commonest tumours followed by lipomas 41 (15.4%) cases. Amongst the total malignant tumours, i.e., 91 (34.08%), rhabdomyosarcoma, 35 (13.1%) was the commonest tumour followed by angiosarcoma 14 (5.2%) cases. Conclusion: Haemangioma is the commonest benign tumour and rhabdomyosarcoma is the commonest malignant tumour in this study.
Keywords: Soft tissues tumours, haemangioma, lipoma, rhabdomyosarcoma, histopathology
References
Rosai J. Akerman. Soft tissues. In: LiVolsi VA, editor. Rosai and Ackerman's Surgical Pathology. 9th ed. St. Louis: Elsevier Mosby,2004. p. 2244-7.
Robbins S, Cotran R. Diseases of the immune system. In: Kumar V, Abbas AK, Sausto N, Aster JC, editors. Robbins and Cotran pathologic basis of disease. 9th ed. Philadelphia: Elsevier Saunders, 2013. p. 791-809.
Umarani MK, Lakra PS, Barathi M. Histopathological spectrum of soft tissue tumors in a teaching hospital. IOSR J Dent Med Sci 2015;1(14):74-80.
Hassawi BA, Abdulkarem Y, Hasan IS. Soft tissue tumors-Histopathological study of 93 cases. Ann Coll Med 2010;36(1&2):92-7.
Jain P, Shrivastava A, Malik R. Clinicomorphological assessment of soft tissue tumors. Sah J App Med Sci 2014;2(2D):886-90.
Batra P, Gupta D, Batra R, Kothari R, Bokariya P. Pattern of soft tissue tumours in a rural population of central india. Innov J Med Health Sci 2013;3(3):124-6.
Janaki M, Arora KVS, Rani S, Kumar MP, Krupal S. Morphological study of soft tissue tumors, Int J Res Health Sci 2015;3(2):364-8.
Agravat AH, Dhruva GA, Parmar SA. Histopathological study of human's soft tissue tumors and tumor like lesions. J Cell Tissue Res 2010;10(2):2287-92.
Sharma M, Khajuria A. Pattern of soft tissue tumors- A histopathological study, JK Sci 2015;17(2):63-7.
Makino Y. A clinicopathological study of soft tissue tumors of the head and neck. Acta Pathol Jpn 1979;29(3):389-408.
Peterson I, Gunther B, Mildner K, Subhi F, Knosel T, Altendorf-Hoffmann A, et al. Update from the soft tissue tumour registry in jena. Pathologe 2011;32(1):40-6.
Bhurqi Y, Bhurqi H, Pervez S, Kayani N, Usman A, Bashir I, et al. Epidemiology of soft tissue sarcoma in Karachi South,Pakistan (1995'‘7). Asian Pac J Cancer Prev 2008;9(4):709-14.
Talati N, Pervez S. Soft tissue sarcomas: Pattern diagnosis or entity? J Pak Med Assoc 1998;48(9):272-5.
Yusuf I, Mohammed AZ, Iliyasu Y. Histopathological study of soft tissue sarcomas seen in a teaching hospital in Kano, Nigeria. Niger J Basic Clin Sci 2013;10(2):70-5.
Hussain N, Verma N. Current concept in pathology of soft tissue sarcoma. Indian J Surg Oncol 2011;2(4):302-8.
Buhari MO, Adigun IA, Rehman GA, Omotayo JA, Ogundipe KO. Soft tissue sarcoma of the head and neck: Description of 27 cases and review of the literature. Res J Med Sci 2009;3(1):19-22
Downloads
Published
How to Cite
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.
