COMPARISON OF POSTOPERATIVE ATRIAL FIBRILLATION IN PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT WITH AND WITHOUT LONG CPB TIME

Authors

  • Ajwad Farogh Shahida Islam Medical College,Lodhran-Pakistan
  • Ahsan Arif Shalamar Institute of Health Sciences, Lahore-Pakistan
  • Noman Izhar Maroof International Hospital Islamabad-Pakistan
  • Saima Jabeen Shalamar Institute of Health Sciences, Lahore-Pakistan
  • Muhammad Ali Shalamar Institute of Health Sciences, Lahore-Pakistan
  • Syeda Rabia Bukhari Punjab Institute of Cardiology, Lahore-Pakistan

DOI:

https://doi.org/10.55519/JAMC-01-12938

Keywords:

Coronary artery bypass grafting, Cardiopulmonary Bypass time, Postoperative Atrial Fibrillation

Abstract

Background: Postoperative atrial fibrillation (POAF) is frequently observed after cardiac surgery, and duration of Bypass Time (CPB) is an independent risk factor for postoperative atrial fibrillation (POAF). The main objective of the current study was to compare new onset Postoperative Atrial Fibrillation (POAF) in patients undergoing coronary artery bypass graft with and without long CPB time. Methods: A prospective comparative study design was used and conducted at the Cardiac Surgery Department in Bahawalpur- Pakistan which is a tertiary care health centre for the period of April 2020 to February 2021, a total of 110 patients were enrolled after getting institutional approval and informed consent from patients. The ethical protocol was followed throughout the study period. Data was entered and analyzed using SPSS version 25.0 and p-value <0.05 taking the level of significant. Results: A total of 110 patients were enrolled for the research, the average age of patients was 48.56±3.11 (age range 30–70), and there were 38(34.55%) & 72(65.45%) male and female patients observed respectively. The atrial fibrillation developed in 3(5.45) patients in without a long CPB time group as compared with the long CPB time group as 8(14.54%) with a statistically significant p-value of 0.043, postoperative IABP support with insignificant p-value of 0.234. Conclusion: Postoperative atrial fibrillation in patients undergoing coronary artery bypass graft is significantly higher with long CPB time as compared with without long CPB time

Author Biographies

Ajwad Farogh, Shahida Islam Medical College,Lodhran-Pakistan

 

Ahsan Arif, Shalamar Institute of Health Sciences, Lahore-Pakistan

 

Noman Izhar, Maroof International Hospital Islamabad-Pakistan

 

Saima Jabeen, Shalamar Institute of Health Sciences, Lahore-Pakistan

 

Muhammad Ali, Shalamar Institute of Health Sciences, Lahore-Pakistan

 

Syeda Rabia Bukhari, Punjab Institute of Cardiology, Lahore-Pakistan

 

References

Dobrev D, Aguilar M, Heijman J, Guichard J-B, Nattel S. Postoperative atrial fibrillation: mechanisms, manifestations and management. Nat Rev Cardiol 2019;16:417–436. 10.1038/s41569-019-0166-5

Mostafa A, El-Haddad MA, Shenoy M, Tuliani T. Atrial fibrillation post cardiac bypass surgery. Avicenna journal of medicine. 2012 Jul;2(03):65-70.

Carter-Storch R, Dahl JS, Christensen NL, Pecini R, Søndergård EV, Øvrehus KA, et al.. Postoperative atrial fibrillation after aortic valve replacement is a risk factor for long-term atrial fibrillation. Interact Cardiovasc Thorac Surg 2019;29:378–385

Filardo G, Pollock BD, da Graca B, Phan TK, Sass DM, Ailawadi G, et al.. Underestimation of the incidence of new-onset post-coronary artery bypass grafting atrial fibrillation and its impact on 30-day mortality. J Thorac Cardiovasc Surg 2017;154:1260–1266.

Gaudino M, Sanna T, Ballman KV, Robinson NB, Hameed I, Audisio K, et al.. Posterior left pericardiotomy for the prevention of atrial fibrillation after cardiac surgery: an adaptive, single-centre, single-blind, randomised, controlled trial. Lancet 2021;398:2075–2083. 10.1016/S0140-6736(21)02490-9

Dave S, Nirgude A, Gujjar P, Sharma R. Incidence and risk factors for development of atrial fibrillation after cardiac surgery under cardiopulmonary bypass. Indian Journal of Anaesthesia. 2018 Nov 1;62(11):887-91.

Schnabel RB, Yin X, Gona P, Larson MG, Beiser AS, McManus DD, Newton-Cheh C, Lubitz SA, Magnani JW, Ellinor PT, Seshadri S. 50 year trends in atrial fibrillation prevalence, incidence, risk factors, and mortality in the Framingham Heart Study: a cohort study. The Lancet. 2015 Jul 11;386(9989):154-62.

Driessen AH, Berger WR, Bierhuizen MF, Piersma FR, van den Berg NW, Neefs J, Krul SP, van Boven WP, de Groot JR. Quality of life improves after thoracoscopic surgical ablation of advanced atrial fibrillation: results of the Atrial Fibrillation Ablation and Autonomic Modulation via Thoracoscopic Surgery (AFACT) study. The Journal of thoracic and cardiovascular surgery. 2018 Mar 1;155(3):972-80.

Hesternzadah K, Dehdlieril Ni, Dehdilani M. Postoperative atrial fibrillation following open cardiac surgery: predisposing factors and compltabons. Journal of cardlovascOar and thoracic research. 2013;5(3)101.

Bohatch Jonlor MS, Matkovski PD, Giovanni Fit, Fardil R, Varela EL, Dietrich A. Incidence of PostOarativa WWI fibrillation in patients undergoing on-pump and off pump coronary artery bypass grants Brazilian Journal of Cardiovascular Surgery. 2D15 Sep;30(3):316-24,

Dave S, Nirgude A, Gujjar P, Sharma R. Incidence and risk factors for development of atrial fibrillation after cardiac surgery under cardiopulmonary bypass. Indian Journal of Anaesthesia. 2018 Nov;62(11):887.

Zakkar M, Ascione R, James AF, Angelini GD, Suleiman MS. Inflammation, oxidative stress and postoperative atrial fibrillation in cardiac surgery. J Stroke Cerebrovasc 2016; 25:1396-402.

Hesternzadah K, Dehdlieril Ni, Dehdilani M. Postoperative atrial fibrillation following open cardiac surgery: predisposing factors and compltabons. Journal of cardlovascOar and thoracic research. 2013;5(3)101.

Bohatch Jonlor MS, Matkovski PD, Giovanni Fit, Fardil R, Varela EL, Dietrich A. Incidence of PostOarativa WWI fibrillation in patients undergoing on-pump and off pump coronary artery bypass grants Brazilian Journal of Cardiovascular Surgery. 2D15 Sep;30(3):316-24,

Rajabi M, Safarpoor G, Borzou SR. Association between incidence of atrial fibrillation and duration of cardiopulmonary bypass in coronary artery bypass graft surgery (CABG): a cohort study. Electronic Physician (ISSN: 2008-5842) 2018;10: 6624-6630

Thoren E, Hellgren L, Stahle E. High incidence of atrial fibrillation after coronary surgery. Interactiv cardiovascular and thoracic surgery 2016;22(2): 176-80.

Additional Files

Published

2024-04-22