FALCIPARUM MALARIA - AN EXPERIENCE WITH 100 CASES
Abstract
Clinical details and present day problems faced in 100 cases of Falciparum Malaria (FM)are reported. Eleven percent had taken chloroquine prior to reporting to us. The parasite densitylacked correlation with the severity of disease. Pattern of fever varied markedly but 10% wereafebrile throughout and presented only with body ache and malaise. Cerebral malaria was presentin 117c patients. Jaundice was present in 187c patients. Other symptoms were vomiting 447c, severeheadache 127c, pain abdomen 77c, loose motions/dysentery 117c, & cough 87c, while bleedingdiathesis was present in 77c (3 meletia, 2 epistaxis, 1 bleeding gums and 1 haematuria). Severeanaemia was present in 107c of cases. Splenomegaly was present in 657c, hepatomegaly 297c andhepatosplenomegaly 217c. Congenital malaria was present in only one (17c) patient. Mild malariapatients were treated with chloroquine, while severe malaria patients were cured with quinine for7 days. Blackwater fever was present in 27c.Patients with Blackwater fever were cured with steroidsand chloroquine. 127c patients had chronic malaria. 837c of these patients presented with anaemia.Self-medication, haphazard therapy and the slogan "Fever May Be Malaria, TakeChloroquine" can lead to problems in Falciparum Malaria. Clinical immunity and parasite strainmay act as virulence factors.References
Strickland GT & Mohyudditi MAZ. Malaria
in the Punjab. Pak J Med Res. 1985, 24; 2: 49-52.
Anand N. In proceedings of the Indo-UK
workshop on malaria, New Delhi, Nov 14-19, 1983.
Malaria Research Centre (ICMR) 1984; 144-67.
Silamut K & White NJ. Relation of stages of
parasite development in peripheral blood to prognosis in
severe Falciparum malaria. Trans Roy Soc Trop Med
Hyg. 1993; 87: 436-43.
Ellis CJ. Diagnosis not to be missed - malaria.
J Applied Med. 1982; 12: 987-89.
Maegraith BG. In Woodruff AW. (Ed).
Medicine in the tropics, London: Churchill Livingstone.
; 27-30.
Shute PG & Maryon M. Imported malaria in
United Kingdom. Br Med J. 1969; 2: 781-85.
Khaliq AA, Fox E, Strickland GT, Latif AZ
& Chaudhry MA. Malaria in rural Punjabi community:
high infection rates with low prevalence of disease. Pak
J Med Res 1985, 24; 2: 69-74.
Rashid A, Ahmad A & Roghami MT.
Falciparum malaria in children. JPMA 1988, 38; 10:
-71.
Purkrittayakamee S, White NJ, Clemens R,
Chittamas S, Karges HE & Desakam U. Activation of
coagulation cascade in Falciparum malaria. Trans Roy
Soc Trop Med Hyg. 1989; 83: 762-66.
Vesama NJ. Intravascular coagulation in
Falciparum malaria. Lancet 1972; 29: 221-23.
Taylor TE, Wirirna JJ, Molyneux ME.
Hypoglycemia and cerebral malaria. Lancet 1990; 336:
-52.
Saeed BO, Atabami GS, Nawaf A &
Abdullah M et al. Hypoglycemia in pregnant women
with cerebral malaria. Trans Roy Soc Trop Med Hyg.
; 84: 349-50.
Krishna S, Waller DW, Kuile FT,
Kwiatkowski D & White NJ et al. Lactic acidosis and
hypoglycemia in children with severe malaria -
pathophysiological and prognostic significance. Trans
Roy Soc Trop Med Hyg 1994; 88: 67-72.
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