INCIDENCE OF CONGENITAL ANOMALIES: A HOSPITAL BASED STUDY
Abstract
During 18 months’ period (January 1994-June 1995), 64 congenitally malformed babies were delivered inObst/Gyn unit of Women and Children Hospital Abbottabad. Incidence was 2.9%. Neural tube defects were42 (65.62%), hydrocephalus 16 (25%), cleft lip and cleft palate 3 (4.68%), amelia one (1.56%), polydactylyone (1.56%) & anophthalmia one (1.56%). 13 (20.3%) mothers were primigravidas, 29 (45.31%) weremultiparas and 22 (34.37%) were grand multiparas. All of them belonged to poor socio-economic class. 9were booked and 55 (85.93%) were un booked. There was no history of X-ray exposure, drugs intake, highgrade fever or congenitally malformed babies. 4 (6.25%) mothers of babies with neural tube defects wereknown diabetics.References
Gentry JT, Parkhurst E & Bulin GV:
Epidemiological study on congenital malformations in New
York state. Am J Public Health 49:497, 1959
Stevenson SS, Worcester J & Rice RG. Six
hundred and seventy-seven congenitally malformed infants
and associated gestational characteristics. Paediatrics 6: 37,
Book JA & Fraccaro M: Research on congenital
malformations. Etud Neonatal 5:39, 1956.
Gregg NM: Congenital cataract following German
measles in mothers. Trans Ophthalmol Soc Aust 3:35, 1984
Milne DB et al (1984). Effect of oral folic acid
supplements on zinc, copper and iron absorption and
excretion. Am J Clin Nutr 39: 535-539
Canton M & Cremin FM (1990). The effect of
dietary zinc depletion and repletion on rats. Br J Nutr 64:201-
MRC Vitamin Study Research Group (1991).
Prevention of Neural Tube Defects. Lancet 338, 131-137
Hurley LS (1981). Teratogenic aspect of
manganese, zinc and copper nutrition. Physiol Rev 61: 249-
Mieden GD et al (1986). Effects of whole rat
embryos culture on serum zinc and copper deficit rats. J Nutr
:2424-2431
Smithells RW, Sheppard S & Wild J (1989).
Prevention of neural tube defects. Lancet ii, 498- 499
McIntosh R et al. Incidence of congenital
malformations. A study of 5964 pregnancies. Paediatrics
:505, 1954
Downloads
Issue
Section
License
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.