LARYNGEAL MUCORMYCOSIS IN AN UNCONTROLLED DIABETIC PATIENT: A CASE REPORT
DOI:
https://doi.org/10.55519/JAMC-03-13598Keywords:
KEYWORDS: Mucormycosis, laryngeal, covid-19, pulmonary,Abstract
Background: With rising conditions in immunocompromised states, the world is facing the challenge of fungal infections with mucormycosis which was rare previously. With the rise in diabetic patients, COVID-19-related immunosuppression, and steroid use, along with an increasing number of transplant and chemotherapy patients, there has been a notable surge in mucorales infections. Although patients with rhino-orbit-cerebral mucormycosis are the most common type of pulmonary rare ones. Methods: Here, we are reporting 1st case of laryngeal mucormycosis in a 55-year-old male presented with respiratory distress in the ENT department of Shaikh Zayed Hospital, Lahore. He had a 4-year history of poorly controlled diabetes, with no other identifiable risk factors. An emergency tracheostomy was performed, pus was aspirated, and necrotic tissue was debrided to relieve the airway obstruction. Conclusion: Laryngeal mucormycosis was diagnosed in the subglottic region via multiple biopsies through direct laryngoscopy under anesthesia. The emergence of new variants of mucormycosis is calling for vigilant identification and meticulous control of predisposing risks. Concomitant debridement and intravenous amphotericin B are recommended under current guidelines.
References
Prakash H, Chakrabarti A. Global epidemiology of Mucormycosis. J Fungi (Basel) 2019;5 Epub 20190321. https://doi.org/10.3390/jof5010026.
Skiada A, Lass-Floerl C, Klimko N, Ibrahim A, Roilides E, Petrikkos G. Challenges in the diagnosis and treatment of mucormycosis. Med Mycol 2018;56:S93-101. https://doi.org/10.1093/mmy/myx101.
Singh AK, Singh R, Joshi SR, Misra A. Mucormycosis in COVID-19: a systematic review of cases reported worldwide and in India. Diabetes Metab Syndr 2021;15:102146 Epub 20210521. https://doi.org/10.1016/j.dsx.2021.05.019.
Ansari R, Dabirmoghaddam P, Lotfi M, Gheitani M, Sohrabpour S, Heidari F. Mucormycosis mimicking tracheal tumor: a case report. Iranian J Med Microbiol 2021;15:247-56. https://doi.org/10.30699/ijmm.15.2.247.
Vandroux D, Allyn J, Ferdynus C, Gauzere BA, Kerambrun H, Galas T et al. Mortality of critically ill patients with severe influenza started four years after the 2009 pandemic. Infect Dis (Lond) 2019;51:831-7 Epub 20190920. https://doi.org/10.1080/23744235.2019.1668957.
Wolf O, Gil Z, Leider-Trejo L, Khafif A, Biderman P, Fliss DM. Tracheal mucormycosis presented as an intraluminal soft tissue mass. Head Neck 2004;26:541-3. https://doi.org/10.1002/hed.20055.
Cornely OA, Arikan-Akdagli S, Dannaoui E, Groll AH, Lagrou K, Chakrabarti A et al. ESCMID and ECMM joint clinical guidelines for the diagnosis and management of mucormycosis 2013. Clin Microbiol Infect 2014;20:5-26. https://doi.org/10.1111/1469-0691.12371.
He R, Hu C, Tang Y, Yang H, Cao L, Niu R. Report of 12 cases with tracheobronchial mucormycosis and a review. Clin Respir J 2018;12:1651-60 Epub 20180219. https://doi.org/10.1111/crj.12724.
Yazicioglu Mocin O, Karakurt Z, Aksoy F, Gungor G, Partal M, Adiguzel N et al. Bronchoscopy as an indicator of tracheobronchial fungal infection in non-neutropenic intensive-care unit patients. Clin Microbiol Infect 2013;19:E136-41 Epub 20130118. https://doi.org/10.1111/1469-0691.12112.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Erum Shahzadi, Ali Shayan, Zia-us-Salam Qazi, Sarfraz Latif, Sohail Ahmad Malik, Usman Chaudhary
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.