MANAGEMENT OF EROSIVE ORAL LICHEN PLANUS ASSOCIATED WITH CHRONIC HEPATITIS C
DOI:
https://doi.org/10.55519/JAMC-03-12370Keywords:
Lichen Planus, Oral; Hepacivirus, Virus Diseases, Pathology, OralAbstract
Hepatic disorders are generally silent, with slow progress, and are usually detected when the organ's function is severely affected. Several studies have shown that oral lichen planus (OLP) is one of the most Hepatitis C-associated diseases. The emergence of such an extrahepatic manifestation is frequent and can lead to an early diagnosis. Patients with chronic hepatitis C virus (HCV) infection exhibit extensive forms of OLP, with frequent periods of exacerbation of symptoms refractory to treatment, which is commensurate with the severity of the liver disease. When treating OLP in HCV patients, researchers have diverged results. This case report presents an extensive, erosive OLP in an HCV-positive female patient for whom clinical management was tremendous. Full remission was obtained after topical corticosteroid application and several sessions of oral cavity sanitation. This clinical case demonstrates that dentists play a major role in OLP diagnosing, managing, and malignant transformation preventing. They may also contribute to the screening of hepatitis C infection.
References
Gheorghe C, Mihai L, Parlatescu I, Tovaru SJM. Association Of Oral Lichen Planus With Chronic C Hepatitis. Review Of The Data In Literature. Maedica (Bucur) 2014;9(1):98-103.
Lodi G, Pellicano R, Carrozzo M. Hepatitis C Virus Infection And Lichen Planus: A Systematic Review With Meta-Analysis. Oral Dis 2010;16(7):601-12.
Baek K, Choi Y. The Microbiology Of Oral Lichen Planus: Is Microbial Infection The Cause Of Oral Lichen Planus? Mol Oral Microbiol 2018;33(1):22-8.
Carozzo M. Oral Health In Patients With Hepatitis C Virus Infection: An Underestimated Problem? Oril Dis 2001;7(5):267-70.
Malik A, Barooah P, Saikia S, Kalita S, Kalita MJ, Das PP, Et Al. Circulating Microrna-122 As A Potential Biomarker For Hepatitis C Virus-Induced Hepatocellular Carcinoma. Int J Cancer Manag 2022;15(11):E131221.
Nagao Y, Kawaguchi T, Ide T, Kumashiro R, Sata M. Exacerbation Of Oral Erosive Lichen Planus By Combination Of Interferon And Ribavirin Therapy For Chronic Hepatitis C. Int J Mol Med 2005;15(2):237-41.
Scully C, Beyli M, Ferreiro MC, Ficarra G, Gill Y, Griffiths M, Et Al. Update On Oral Lichen Planus: Etiopathogenesis And Management. Crit Rev Oril Biol Med 1998;9(1):86-122.
Carrozzo M, Porter S, Mercadante V, Fedele S. Oral Lichen Planus: A Disease Or A Spectrum Of Tissue Reactions? Types, Causes, Diagnostic Algorhythms, Prognosis, Management Strategies. Periodontol 2019;80(1):105-25.
Lodi G, Scully C, Carrozzo M, Griffiths M, Sugerman PB, Thongprasom K. Current Controversies In Oral Lichen Planus: Report Of An International Consensus Meeting. Part 1. Viral Infections And Etiopathogenesis. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2005;100(1):40-51.
Crowley D, Van Hout MC, Lambert JS, Kelly E, Murphy C, Cullen W. Barriers And Facilitators To Hepatitis C (HCV) Screening And Treatment-A Description Of Prisoners' Perspective. Harm Reduct J 2018;15(1):1-10.
Carrozzo M, Scally K. Oral Manifestations Of Hepatitis C Virus Infection. World J Gastroenterol 2014;20(24):7534-43.
Sagi L, Baum S, Agmon-Levin N, Sherer Y, Katz BS, Barzilai O, Et Al. Autoimmune Bullous Diseases The Spectrum Of Infectious Agent Antibodies And Review Of The Literature. Autoimmun Rev 2011;10(9):527-35.
Carrozzo M. Oral Diseases Associated With Hepatitis C Virus Infection. Part 2: Lichen Planus And Other Diseases. Oral Dis 2008;14(3):217-28.
Alaizari N, Al-Maweri S, Al-Shamiri H, Tarakji B, Shugaa-Addin B. Hepatitis C Virus Infections In Oral Lichen Planus: A Systematic Review And Meta-Analysis. Aust Dent J 2016;61(3):282-7.
Pitak-Arnnop P, Subbalekha K, Sirintawat N, Tangmanee C, Auychai P, Muangchan C, Et Al. Are Oral Lichen Planus Patients At High Risk Of Hepatitis C? A Case-Control Study. J Stomatol Oral Maxillofac Surg 2021;123(3):E37-42.
Roudot-Thoraval F. Epidemiology Of Hepatitis C Virus Infection. Clin Res Hepatol Gastroenterol 2021;45(3):101596.
Lahlali M, Abid H, Lamine A, Lahmidani N, El Yousfi M, Benajah D, Et Al. Epidemiology Of Viral Hepatitis In The Maghreb. Tunis Med 2018;96(10-11):606-19.
Khedhiri M, Triki H, Triki H. Hepatitis C In Tunisia From 1991 To 2019: A Systematic Review. Tunis Med 2021;99(2):189-200.
Ibrahim HA, Baddour MM, Morsi MG, Abdelkader AA. Should We Routinely Check For Hepatitis B And C In Patients With Lichen Planus Or Cutaneous Vasculitis? 1999;5(1):71-8.
Ko HM, Hernandez-Prera JC, Zhu H, Dikman SH, Sidhu HK, Ward SC, Et Al. Morphologic Features Of Extrahepatic Manifestations Of Hepatitis C Virus Infection. Clin Dwv Immunol 2012;2012:740138.
Mouelhi L, Debbeche R, Sfar I, Salem M, Bouzaidi S, Trabelsi S, Et Al. Auto-Immune Serological Disorders In Chronic Viral C Hepatitis: Prevalence And Clinical Significance. Tunis Med 2008;86(9):777-81.
Beaird LM, Kahloon N, Franco J, Fairley JA. Incidence Of Hepatitis C In Lichen Planus. J Am Acad Dermatol 2001;44(2):311-2.
Carrozzo M, Gandolfo S. The Management Of Oral Lichen Planus. Oral Dis 1999;5(3):196-205.
Vincent S, Fotos P, Baker K, Williams T. Oral Lichen Planus: The Clinical, Historical, And Therapeutic Features Of 100 Cases. Oral Surg Oral Med Oral Pathol 1990;70(2):165-71.
Carrozzo M, Thorpe Rjms. Oral Lichen Planus: A Review. Minerva Stomatol 2009;58(10):519-37.
Emslie E, Hardman FG. The Surgical Treatment Of Oral Lichen Planus. Trans St Johns Hosp Dermatol Soc 1970;56(1):43-4.
Amanat D, Ebrahimi H, Zahedani MZ, Zeini N, Pourshahidi S, Ranjbar Z. Comparing The Effects Of Cryotherapy With Nitrous Oxide Gas Versus Topical Corticosteroids In The Treatment Of Oral Lichen Planus. Indian J Dent Res 2014;25(6):711-6.
Guiglia R, Di Liberto C, Pizzo G, Picone L, Lo Muzio L, Gallo P, Et Al. A Combined Treatment Regimen For Desquamative Gingivitis In Patients With Oral Lichen Planus. J Oral Pathol Med 2007;36(2):110-6.
Mester A, Lucaciu O, Ciobanu L, Apostu D, Ilea A, Campian RS. Clinical Features And Management Of Oral Lichen Planus (OLP) With Emphasis On The Management Of Hepatitis C Virus (HCV)-Related OLP. Bosn J Basic Med Sci 2018;18(3):217-23.
Soliman M, El Kharbotly A, Saafan A. Management Of Oral Lichen Planus Using Diode Laser (980 Nm): A Clinical Study. Ehypt Dermatol Online J 2005;1(1):3.
Cafaro A, Albanese G, Arduino PG, Mario C, Massolini G, Mozzati M, Et Al. Effect Of Low-Level Laser Irradiation On Unresponsive Oral Lichen Planus: Early Preliminary Results In 13 Patients. Photomed Laser Surg 2010;28(Suppl 2):S99-103.
Van Der Hem P, Egges M, Van Der Wal J, Roodenburg J. CO2 Laser Evaporation Of Oral Lichen Planus. Int J Oral Maxillofac Surg 2008;37(7):630-3.
Trehan M, Taylor CR. Low-Dose Excimer 308-Nm Laser For The Treatment Of Oral Lichen Planus. Arch Dermatol 2004;140(4):415-20.
Scelza G, Amato A, Pagano AM, De Matteis G, Caruso R, Scelza A, Et Al. Effect Of Hepatitis C Antiviral Therapy On Oral Lichen Planus And Hyposalivation In Inmates. Ann Gastroenterol 2022;35(1):74-9.
Lu SY, Lin LH, Lu SN, Wang JH, Hung CH. Increased Oral Lichen Planus In A Chronic Hepatitis Patient Associated With Elevated Transaminase Levels Before And After Interferon/Ribavirin Therapy. J Dent Sci 2009;4(4):191-7.
Nagao Y, Kimura K, Kawahigashi Y, Sata M. Successful Treatment Of Hepatitis C Virus-Associated Oral Lichen Planus By Interferon-Free Therapy With Direct-Acting Antivirals. Clin Transl Gastroenterol 2016;7(7):E179.
Scott GD, Rieger Kejjocp. New-Onset Cutaneous Lichen Planus Following Therapy For Hepatitis C With Ledipasvir-Sofosbuvir. 2016;4(43):408-9.
Nagao Y, Tsuji MJ. Effects Of Hepatitis C Virus Elimination By Direct-Acting Antiviral Agents On The Occurrence Of Oral Lichen Planus And Periodontal Pathogen Load: A Preliminary Report. Int J Dent 2021;2021:8925879.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Taissir Medini, Amira Besbes, Wafa Nasri, Nouha L Ben Abdeljelil, Jamil Selmi
This work is licensed under a Creative Commons Attribution-NoDerivatives 4.0 International License.
Journal of Ayub Medical College, Abbottabad is an OPEN ACCESS JOURNAL which means that all content is FREELY available without charge to all users whether registered with the journal or not. The work published by J Ayub Med Coll Abbottabad is licensed and distributed under the creative commons License CC BY ND Attribution-NoDerivs. Material printed in this journal is OPEN to access, and are FREE for use in academic and research work with proper citation. J Ayub Med Coll Abbottabad accepts only original material for publication with the understanding that except for abstracts, no part of the data has been published or will be submitted for publication elsewhere before appearing in J Ayub Med Coll Abbottabad. The Editorial Board of J Ayub Med Coll Abbottabad makes every effort to ensure the accuracy and authenticity of material printed in J Ayub Med Coll Abbottabad. However, conclusions and statements expressed are views of the authors and do not reflect the opinion/policy of J Ayub Med Coll Abbottabad or the Editorial Board.
USERS are allowed to read, download, copy, distribute, print, search, or link to the full texts of the articles, or use them for any other lawful purpose, without asking prior permission from the publisher or the author. This is in accordance with the BOAI definition of open access.
AUTHORS retain the rights of free downloading/unlimited e-print of full text and sharing/disseminating the article without any restriction, by any means including twitter, scholarly collaboration networks such as ResearchGate, Academia.eu, and social media sites such as Twitter, LinkedIn, Google Scholar and any other professional or academic networking site.
