ALT CHANGES AND ADVERSE EVENTS OF TELBIVUDINE IN HEPATITIS-B PATIENTS-AN EXPERIENCE OF 11 PATIENTS

Authors

  • Zeeshan Ali
  • Neeta Maheshwary
  • Uffaq Zara
  • Siddiqi Ahson
  • Muhammad Athar Khan

Abstract

Hepatitis-B virus (HBV) infection is a major global health problem. Of the two billion people who have been infected, more than 350 million have chronic hepatitis. It is estimated that 235,000-328,000 people die annually due to liver cirrhosis and hepatocellular carcinoma, we assessed the short term outcomes of treatment with telbivudine in 11 adults aged 14-41 years with HBeAg-positive or HBeAg-negative chronic hepatitis-B (CHB). Treatment of chronic hepatitis-B patients with telbivudine shows 43.1% reduction in serum ALT with no significant adverse effects.

Keywords: Telbivudine, Hepatitis-B Virus, Hepatocellular Carcinoma, HBeAg

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Published

2015-03-01

How to Cite

Ali, Z., Maheshwary, N., Zara, U., Ahson, S., & Khan, M. A. (2015). ALT CHANGES AND ADVERSE EVENTS OF TELBIVUDINE IN HEPATITIS-B PATIENTS-AN EXPERIENCE OF 11 PATIENTS. Journal of Ayub Medical College Abbottabad, 27(1), 241–2. Retrieved from https://demo.ayubmed.edu.pk/jamc/index.php/jamc/article/view/1153