EFFECTS OF RAMADAN FASTING ON BLOOD PRESSURE IN NORMOTENSIVE MALES

Authors

  • Fatima Samad Department of Community Health Sciences, Aga Khan University, Karachi
  • Fahd Qazi Department of Community Health Sciences, Aga Khan University, Karachi
  • Mohammad B Pervaiz Department of Community Health Sciences, Aga Khan University, Karachi
  • Danesh K Kella Department of Community Health Sciences, Aga Khan University, Karachi
  • Maryah Mansoor Department of Community Health Sciences, Aga Khan University, Karachi
  • Bushra Z Osmani Department of Community Health Sciences, Aga Khan University, Karachi
  • Fazia Mir Department of Community Health Sciences, Aga Khan University, Karachi
  • Muhammad Masood Kadir Department of Community Health Sciences, Aga Khan University, Karachi

Abstract

Background: Research has been done to investigate the effect of intermittent complete fasting on human physiological parameters but the effect of fasting on blood pressure remains relatively unexplored. Research in animal models suggests a hypotensive effect with an undetermined mechanism. Muslims worldwide fast daily from dawn to dusk throughout the Islamic month of Ramadan. This study was to investigate the proposed hypotensive effect of Ramadan fasting in males over a period of 20 days and to study the relationship of the pattern of blood pressure variation with body mass index change. Methods: A repeated measures observational study design was implemented with convenient sampling. Study group included 40 normotensive, non-smoker males with no known comorbidities between the ages of 18–40 who fasted daily in the month of Ramadan. One set of BP readings, each, was taken one week before the start of Ramadan and on the 7th, 14th and 21st day of Ramadan which included pre and post Iftar measurements along with other variables. Data was analysed by repeated measures ANOVA using SPSS. The differences were compared with critical values generated by Tukey’s Method. Results: There was a significant drop in systolic BP of 7.61 mmHg before Iftar, 2.72mmHg after Iftar (p<0.005). There was a significant effect of Ramadan on diastolic BP (p<0.005), the drop being 3.19 mmHg. The drop in body mass index was significant only before Iftar at 0.3kg/m2 (p<0.005). Pulse rate showed a significant drop of 7.79 bpm before Iftar and a significant rise of 3.96 bpm (p<0.005). Conclusions: Intermittent fasting causes a drop in both systolic and diastolic blood pressure in normotensive males.Keywords: Ramdan, Iftar, Normotensive, Fasting, Body Mass Index

References

Bouguerra R, Belkadhi A, Jabrane J, Hamzaoui J, Maâtki C, Ben Rayana MC, et al. [Metabolic effects of the month of Ramadan fasting on type 2 diabetes]. East Mediterr Health J ;9(5–6):1099–108.

Bouguerra R, Jabrane J, Maâtki C, Ben Salem L, Hamzaoui J, El Kadhi A, et al. Ramadan fasting in type 2 diabetes mellitus. Ann Endocrinol (Paris) 2006;67(1):54–9.

Kassem HS, Zantout MS, Azar ST. Insulin therapy during Ramadan fast for Type 1 diabetes patients. J Endocrinol Invest 2005;28(9):802–5.

Bogdan A, Bouchareb B, Touitou Y. Ramadan fasting alters endocrine and neuroendocrine circadian patterns. Meal-time as a synchronizer in humans? Life Sci 2001;68(14):1607–15.

Khaled BM, Bendahmane M, Belbraouet S. Ramadan fasting induces modifications of certain serum components in obese women with type 2 diabetes. Saudi Med J 2006;27(1):23–6.

Lamine F, Bouguerra R, Jabrane J, Marrakchi Z, Ben Rayana MC, Ben Slama C, et al. Food intake and high density lipoprotein cholesterol levels changes during Ramadan fasting in healthy young subjects. Tunis Med 2006;84(10):647–50.

Roky R, Houti I, Moussamih S, Qotbi S, Aadil N. Physiological and chronobiological changes during Ramadan intermittent fasting. Ann Nutr Metab 2004;48(4):296–303.

Al Suwaidi J, Bener A, Hajar HA, Numan MT. Does hospitalization for congestive heart failure occur more frequently in Ramadan: a population-based study (1991–2001). Int J Cardiol 2004;96(2):217–21.

Chamsi-Pasha H, Ahmed WH. The effect of fasting in Ramadan on patients with heart disease. Saudi Med J 2004;25(1):47–51.

Temizhan A, Donderici O, Ouz D, Demirbas B. Is there any effect of Ramadan fasting on acute coronary heart disease events? Int J Cardiol 1999;70(2):149–53.

Perk G, Ghanem J, Aamar S, Ben-Ishay D, Bursztyn M. The effect of the fast of Ramadan on ambulatory blood pressure in treated hypertensives. J Hum Hypertens 2001;15(10):723–5.

Habbal R, Azzouzi L, Adnan K, Tahiri A, Chraibi N. [Variations of blood pressure during the month of Ramadan]. Arch Mal Coeur Vaiss 1998;91(8):995–8.

Dewanti L, Watanabe C, Sulistiawati, Ohtsuka R. Unexpected changes in blood pressure and hematological parameters among fasting and nonfasting workers during Ramadan in Indonesia. Eur J Clin Nutr 2006;60(7):877–81.

Husain R, Duncan MT, Cheah SH, Chng SL. Effects of fasting in Ramadan on tropical Asiatic Moslems. Br J Nutr 1987;58(1):41–8.

Rahman M, Rashid M, Basher S, Sultana S, Nomani MZ. Improved serum HDL cholesterol profile among Bangladeshi male students during Ramadan fasting. East Mediterr Health J 2004;10(1–2):131–7.

Einhorn D, Young JB, Landberg L. Hypotensive effect of fasting: possible involvement of the sympathetic nervous system and endogenous opiates. Science 1982;217(4561):727–9.

Hunt LM, Hogeland EW, Henry MK, Swoap SJ. Hypotension and bradycardia during caloric restriction in mice are independent of salt balance and do not require ANP receptor. Am J Physiol Heart Circ Physiol 2004;287(4):H1446–51.

Koppeschaar HP, Meinders AE, Schwarz F. The effect of modified fasting on blood pressure and sympathetic activity: a correlation? Int J Obes 1983;7(6):569–74.

Laurent S. Very-low-dose combination of perindopril and indapamide: efficacy on blood pressure and target-organ damage. J Hypertens Suppl 2003;21(3):S11–8.

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Published

2015-06-20

Issue

Vol. 27 No. 2 (2015): Journal of Ayub Medical College, Abbottabad

Section

ORIGINAL ARTICLE

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